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CLIP-seq Kit

CLIP-seq obtains purified and digested (Protease K, DNase I, RNase T1) RNA by immunoprecipitating the binding complex of RBP and RNA, and performs cDNA library construction and sequencing analysis.

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PRODUCT INFORMATION

Product introduction：

CLIP is an important technology that uses the covalent cross-linking of protein and RNA under 365 nm ultraviolet light to study the interaction of protein and RNA.CLIP-seq obtains purified and digested (Protease K, DNase I, RNase T1) RNA by immunoprecipitating the binding complex of RBP and RNA, and performs cDNA library construction and sequencing analysis.(This kit is for scientific research purposes only)

Technical process：

Product features：

1.After ultraviolet irradiation, the RNA in the cell is cross-linked with the corresponding RNA-binding protein to enhance the binding ability of RNA and protein.
2.Can detect a variety of RNA, such as lncRNA, mRNA, microRNA.
3.CLIP-seq can accurately locate the binding site of RNA and protein.

4.Have independent intellectual property rights.

Instructions

Bes3014-1 CLIP-qPCR

Bes3014-2 CLIP-seq

Articles

【In 2023】

Article：The CTBP2-PCIF1 complex regulates m6Am modification of mRNA in head and neck squamous cell carcinoma

Periodicals：The Journal of Clinical Investigation

IF：15.900

Article：CircFOXP1 alleviates brain injury after acute ischemic stroke by regulating STAT3/apoptotic signaling

Periodicals：Translational Research

IF：10.171