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chromosome conformation capture (3C) is an innovative tool for mapping chromatin interactions....
Cleavage Under Target & Tagmentation (CUT&Tag) is an emerging method of studying DNA-protein interaction....
ChIP is currently the best method to determine the genomic region that binds to a specific protein, or to determine the protein that binds to a specific genomic region....
DNA pulldown is a technique used to study the interaction between DNA and protein....
The biotin-labeled miRNA probe is transfected into cells, and the biotin-labeled miRNA-RNA complex in the cell lysate can be efficiently enriched with streptavidin magnetic beads....
Modification of genomic DNA with bisulfite, all unmethylated cytosine (C) is converted to uracil (U), while the methylated cytosine remains unchanged, resulting in a change in the base ratio of genomic DNA ....
A specific probe is designed for the target area and labeled with biotin.The end-labeled nucleic acid probe can bind to the protein. During electrophoresis, the probe and the protein complex move slowly in the gel, that ......
A specific probe is designed for the target area and labeled with biotin.The end-labeled nucleic acid probe can bind to the protein. During electrophoresis, the probe and the protein complex move slowly in the gel, that ......
According to different research objects, RAP technology combines high-throughput sequencing (RAP-Seq) and mass spectrometry (RAP-MS) to study the genes and proteins that interact with target RNA....
RNA methylation refers to the methylation modification phenomenon that occurs at different positions on the RNA molecule. The common methods of RNA post-transcriptional modification include m6A and m5C....
According to different research objects, ChIRP technology combines high-throughput sequencing (ChIRP-Seq) and mass spectrometry (ChIRP-MS) to study the genes and proteins that interact with target RNA....
A specific RNA probe labeled with desthiobiotin is designed for the target area and incubated with cell protein extracts.The target RNA probe-protein complex is obtained by coupling magnetic beads and eluting....
RIP is a powerful tool to understand the dynamic process of post-transcriptional regulatory networks. It can be applied to study miRNA regulatory targets, the interaction between RNA and RBPs, etc....
Reverse-ChIP can comprehensively and systematically identify proteins related to target DNA sites, especially looking for regulatory proteins corresponding to known DNA elements....
MeDIP enriches highly methylated DNA fragments with 5mC antibody, and uses downstream nucleic acid detection technology to detect methylation sites in the whole genome....